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Thyroid School Issue #21// Thyroid + Brain Health

September 9, 2022

The thyroid gland and the brain have a close-knit relationship. This two-way street of communication helps to maintain hormonal harmony in the body. When circulating levels of thyroid hormone are low, the brain (via the hypothalamus and pituitary gland) secrete TRH and then TSH to stimulate the thyroid to produce more hormones until proper amounts are reached in circulation. This is why TSH levels are inversely associated with thyroid status— meaning the higher the number, the more hypothyroid. As with any relationship, this open communication is imperative to maintain the status as “in a relationship” instead of “it’s complicated”. When either party begins to disrupt communication, the relationship will struggle. Common reasons for brain-thyroid communication interruptions: Autoimmunity: One of the most common reasons(upwards of 95% of the time) for this includes thyroid damage related to Hashimoto’s (autoimmunity) in which the inflammatory damage is too great for the thyrocytes (cells in the thyroid) to properly produce adequate amounts of thyroid hormone. No matter how hard the brain works to produce TSH and stimulate the thyroid, the thyroid just can’t perform the task. HPA Axis dysfunction: the HPA-Axis stands for the hypothalamus, pituitary, and adrenal axis. This brain-adrenal axis communicates directly to the thyroid gland. Stress...

Thyroid School: Issue 8// Autoimmunity

November 5, 2021

Last Thyroid School email, I reviewed how to tell the difference between whether your hypothyroidism is autoimmune in nature or not. To review, autoimmunity is a problem when your immune... Read More